Beta-Caryophyllene

• Aroma: Woody, spicy, peppery [12] 

• Effects: Improves moods and a general sense of well-being.

• Pharmacological Properties Include:  Antispasmodic activity [1, 2, 9, 11], antiviral [1], antidepressant [1, 9, 14, 54], analgesic [2, 9, 10, 14], anti-inflammatory [2, 3, 9, 10, 15, 56], anti spasmic in gut muscles [2], gastroprotective [3, 9, 10, 11, 14, 56], antioxidant [9, 10, 14, 56], antiviral [9], local anesthetic [9], antifungal [9, 10, 14, 15], anticancer [9, 10, 12, 14], antimalarial [9], antipruritic [9], anxiolytic [9, 10, 54], neuroprotective [10, 14], antibacterial [10, 14], antiarthritic [51], anticonvulsant [54, 57], cardio protectant [56], hepatoprotective [56], antimicrobial [56], and immune-modulatory [56].   

• Beta-Caryophyllene May Benefit these Diseases or Symptoms: May help with malaria [1, 2, 9, 11], HPV (Human Papilloma Virus) [1, 14], depression [1, 9, 12, 54], neuropathic pain (peripheral neuropathy) [9, 15], antibacterial against staphylococcus aureus [9], inflammatory bowel disease [9, 15], dermatitis (itching) [9], anxiety [9, 54], brain [12], cervical adenocarcinoma [38], head and neck [12], liver [12], lung [12], breast [12, 38], lymphoma [38], melanoma [38, 39], bladder [12, 41], ovarian [12, 38, 40], osteosarcoma [12], skin- epidermoid [12], pancreatic [12, 38], and prostate [12, 38, 44, 45] cancers, when combined with humulene may help with cancer for liver [12] and colon [12, 38, 42, 43] cancers, antifungal for Candida glabrata, Candida albicans, and Aspergillus niger [15], multiple sclerosis [15], Parkinson’s disease for antioxidant [46], protect against dementia induced by neuro-inflammation with no effect on neuronal aging induced by mitochondrial dysfunction [47], neuro-inflammation and Alzheimer’s disease [48], may show promise with COVID-19 [49], Herpes simplex virus [50], osteoarthritis [51], gouty arthritis [52], obesity, type II diabetes (T2D), cardiovascular disease (CVD), seizures, non-alcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH) liver diseases [53], seizures [54, 57], lowered Helicobacter pylori (bacterial infection) which helped with nausea and epigastric pain for gastrointestinal treatment [55], and cognitive impairment with multiple sclerosis [58].

• Also Found In: Black and white pepper, cloves, oregano, basil, chamomile, bay leaves, rosemary, black caraway, and cinnamon [9].

• Warning: In isolates, this chemical irritates the skin, but has a considerable safe profile [59].